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Advanced Age Infertility ZIFT

Posted on November 21, 2015

Old Procedure Still Showing Promise for Advanced Age Infertility, ZIFT

When I started my fertility journey I assumed like so many others since there was no family history of infertility I would have success on my first attempt at IVF.  Was I ever so wrong! After multiple failed cycles I knew I needed change. I was about to relocate permanently to Southern California and knew I would find the change I so desperately needed there. Southern California is what I like to refer to as, “home to the leading legends of fertility treatment”  some of the worlds best reproductive endocrinologist. Don’t get me wrong South Florida is also home to some of the worlds best clinics in the country. My problem I was relocating to California for work and had to leave Florida behind.

Once I was ready to regroup and cycle again I made a list of all the clinics I was going to visit and consult with in Southern California. You name it, California Fertility Partners, USC, Santa Monica Fertility and the list goes on. What I found interesting at the time was that USC and Santa Monica Fertility were big on an old school procedure that was showing promise for women 40+ that were still hoping to utilize their own eggs to have a biological child of their own. USC under the direction of Dr. Paulson was offering a clinical trial comparing traditional IVF vs Zift. You ask what is ZIFT?  With ZIFT, fertilized eggs called zygotes, are placed in the women’s fallopian tubes after they’ve been fertilized in a lab via in -vitro fertilization (IVF). In traditional IVF, fertilized eggs are implanted in a woman’s uterus after they grow for 3 to 5 days in the lab. In ZIFT, several fertilized eggs are surgically placed through a laparoscopy surgical procedure directly into a woman’s fallopian tube(s) within 24 hours of fertilization.

Why Zift?  I asked the same question. Interesting enough I learned that many Dr’s don’t use this technique anymore because it requires a women to go through a traditional IVF cycle with an egg retrieval and then within 24 hours after fertilization of the eggs another surgery requiring them to go under general anesthesia as well as laparocopic surgery. The good thing that I learned after meeting with Dr. John Jain at Santa Monica Fertility was that he was showing great success with this procedure and women with advanced aged infertility. Dr. Jain explained to me that, ” when a women is older they find that the embryos thrive much better in their natural environment which is the fallopian tube and not a petri dish.”  Right then I knew I had found the change I needed and was ready for my attempt at a ZIFT.

What are the requirements to move forward with a ZIFT cycle? If utilizing your own eggs then the production of enough eggs to go through a traditional IVF cycle. A women with at least one working fallopian tube who hasn’t been able to conceive during a regular IVF cycle. With ZIFT, several fertilized eggs are placed in the fallopian tube(s). If all goes well, in the process, the fertilized eggs travel down the fallopian tube(s) and implant in the woman’s uterus, and the fetus develops.I attempted this procedure twice with my own eggs. Yes, I did have success on both attempts, but neither latest very long. Fast forward to my final cycle and now using an egg donor. I still stuck to the ZIFT protocol and finally had great success on my final cycle, “16” to conceive my golden egg, Bryce. Dr. Jain  presented his ZIFT findings at the Pacific Coast Reproductive Society meeting demonstrating pregnancy rates over 40% in the group of women over 40 years old. Take the time and watch this YouTube video.

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