How to administer medications correctly.

For Surrogates

Surrogate Medications

Several different medications are required to be taken by the surrogate mother to prepare her uterus to accept the embryo for implantation and to sustain the pregnancy. All of these medications will be explained at length with you at the Fertility clinic.

Lupron (leuprolide acetate)

This medication is used to turn off your body’s own natural stimulation to your ovaries. Lupron temporarily turns off your brain’s natural release of follicle stimulating hormone (FSH) and luteinzing hormone (LH), inducing a medical menopause. This medication is used in a way to help the doctor establish a baseline level or in other words a starting point. This is the first medication given to a surrogate other then birth control. Administration: Lupron is administered by subcutaneous (SQ) injection, meaning a small needle inserted under the skin. Side Effects: No long-term side effects have been reported

  • Moodiness/Irritability
  • Headache
  • Hot Flashes
  • Insomnia
  • Local irritation at the site of the injection
Vivelle Patches (estradiol transdermal)

Estrogen is a hormone that helps maintain an early pregnancy Administration: Patches are placed on the abdomen and estrogen is absorbed through the skin. Estrogen can also be given in pill form. Side Effects

  • Skin redness/irritation at the application site
  • Nausea
  • Bloating
  • Breast tenderness
  • Headache
  • Weight change

Progesterone is a hormone that is necessary to prepare the uterus lining for the implantation of the embryo and to help support and maintain an early pregnancy. Administration is either in the form of a vaginal suppository or intramuscular injection Side Effects

  • Irritability
  • Breast tenderness
Aspirin (baby aspirin)

Assist with cycle stimulation and embryo implantation Typically this medication is used for the first trimester Administration 81-83 mg low-dose baby aspirin taken orally Side effects

  • None

Treats any possible low-grade pelvic or prostate infection. This is given as a pre-cycle antibiotic to both the surrogate mother and partner.


This antibiotic is taken starting several days before the embryo transfer to prevent infection from occurring Administration orally taken in pill form Side effects

  • sun sensitivity
  • upset stomach